Klinische Studien
VARIHESIVE® Verbände
Die Anwendung der VARIHESIVE®-Wundverbände bietet nachweisliche Vorteile zur Unterstützung der Wundheilung.
Im Vergleich zu herkömmlichen Wundverbänden und anderen Hydrokolloid-Wundverbänden wurde mit Varihesive-Wundverbänden eine bessere Heilung chronischer Wunden beobachtet.
There is evidence that wound improvement is more likely with GranuFLEX® and DuoDERM® Dressings than other hydrocolloids in the management of pressure sores.
In a prospective, controlled multicenter clinical study of 52 patients it was observed that:3
41 of 52 patients had improved wounds when DuoDERM® dressings were used as compared with 31 of 51 patients managed with Tegasorb™a (a hydrocolloid dressing).
In a meta-analysis of the randomized controlled trials (RCT) on hydrocolloid occlusive dressings versus conventional gauze in the healing of chronic wounds: 4
Analysis of the 11 papers that met the inclusion criteria found that complete healing occurred in 51% of ulcers in the hydrocolloid group as compared to 38% in the conventional group.
A review of economic studies in wound care management demonstrated that GranuFLEX® and DuoDERM® Dressings can reduce the overall cost of care and is cost-effective for the management of pressure sores and leg ulcers.
Eine Übersicht von gesundheitsökonomischen Untersuchungen im Bereich der Wundversorgung hat gezeigt, dass VARIHESIVE®-Wundverbände die Gesamtkosten der Patientenversorgung verringern können und eine kostengünstige Maßnahme beim Management von Druckgeschwüren und Ulcus cruris darstellen.
A cost study by Kerstein et al 5 concluded that:
The cost per venous ulcer healed over 12 weeks was lower for GranuFLEX® and DuoDERM® Dressings than impregnated gauze dressings.
GranuFLEX® and DuoDERM® Dressings were more cost-effective than competitor hydrocolloids and saline gauze in the treatment of pressure ulcers over a 12 week period
The European Pressure Ulcer Advisory Panel (EPUAP) and The National Pressure Ulcer Advisory Panel (NPUAP) guidelines recommend the usage of hydrocolloids for the management of pressure ulcers.
Category/stage 1: Intact skin with non-blanchable redness of localized area, usually over a bony prominence. Darkly pigmented skin may not have visible blanching; its color may differ from the surrounding area.
"Consider using hydrocolloid dressings to protect body areas at risk for friction injury or risk of injury from tape. (Strength of Evidence=C)"
Category/stage 2: Partial thickness loss of dermis presenting as a shallow open ulcer with a red/pink wound bed, without slough. It may also present as an intact or open/ruptured serum-filled blister.
"Use hydrocolloid dressings for clean Category/Stage II pressure ulcers in body areas where they will not roll or melt. (Strength of Evidence=B)"
a Tegasorb™ is a trademark of the 3M Company.
- Cordts PR, Hanrahan LM, Rodriguez AA, Woodson J, LaMorte WW, Menzoian JO. A prospective, randomized trial of Unna's boot versus Duoderm CGF hydroactive dressing plus compression in the management of venous leg ulcers.[see comment]. Journal of Vascular Surgery. 1992 Mar;15(3):480-6.
- Hansson C. The effects of cadexomer iodine paste in the treatment of venous leg ulcers compared with hydrocolloid dressing and paraffin gauze dressing. Cadexomer Iodine Study Group. International Journal of Dermatology. 1998 May;37(5):390-6.
- Day A, Dombranski B, Farkas C, et al. Managing sacral pressure ulcers with hydrocolloid dressings: Results of a controlled clinical study. Ostomy/Wound Management. 1995; 41: 52-65.
- Singh A, Halder S, Menon GR, et al. Meta-analysis of Randomized Controlled Trials on hydrocolloid occlusive dressings versus conventional gauze dressing in the healing of chronic wounds. Asian Journal of Surgery. Vol 27, No . 4, October 2004.
- Kerstein M D, Gemmen E, Van Rijswijk L, Lyder CH, Phillips T, Xakellis G, Golden K, Harrington C. The cost and cost effectiveness of Venous and Pressure Ulcer Protocols of Care. Disease Management and Health Outcomes. 2001;9(11):651-663.
- Harding K, Cutting K, Price P. The cost-effectiveness of wound management protocols of care. Br J Nursing. 2000, (suppl) Vol 9, No. 19.
- Meaume S, Gemmen E. Cost effectiveness of wound management in France: pressure ulcers and venous leg ulcers. Journal of Wound Care. Vol 11, No. 6, June 2002.